Showing posts with label Research. Show all posts
Showing posts with label Research. Show all posts

Sunday, July 29, 2012

Nothing natural about DMAA Research Supplement:

Wednesday, July 25, some manufacturers HealthDay News)-sports supplements are falsely claiming that a compound known as DMAA is a natural material extracted from geraniums, the researchers say.

Instead, research shows that artificial, consisting of the DMAA is four compounds called stereoisomers.

DMAA (1,3-dimethylamylamine) is an invigorating sports nutrition supplements number found. The investigators analyzed eight different from plants growing in a variety of essential geranium areas, none of the traces of the DMAA. In addition, the chemical make-up of the so-called natural plant derived DMAA was identical to that of synthetic DMAA responsibility.

The researchers concluded DMAA found in supplements may not have a plant geranium.

"The FDA should regulate or forbid other products of significant amounts of synthetic compounds for pharmacological research," said author Daniel Armstrong, University of Texas at Arlington, the journal news release. "In addition, this information should be clearly labeled, including potential side effects, and their effects so that consumers can make an informed choice decision."

Recently published research, analysis, drug tests.

DMAA is the question of safety in recent years. In 2011, following the deaths of two soldiers who were United States heart attacks during training exercises and removed was the Department of Defense, DMAA United States supplements that contain DMAA its stores on military bases.

-Mary Elizabeth Dallas MedicalNews copyright © HealthDay 2012. All rights reserved. Source: Wiley-Blackwell, press release, July 2012



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Saturday, June 16, 2012

Is obstructive sleep apnea associated with cortisol levels? A systematic review of the research evidence

a San Diego State University & University of California, San Diego, Joint Doctoral Program in Clinical Psychology, San Diego, UCSD Mail Code 0804, La Jolla, CA, United Statesb Department of Psychiatry, University of California, San Diego, CA, United StatesReceived 8 March 2011. Revised 21 May 2011. Accepted 23 May 2011. Available online 30 July 2011.View full text The pathophysiology of obstructive sleep apnea (OSA) has been associated with dysregulation of the hypothalamic pituitary adrenal (HPA) axis; however a relationship between OSA and altered cortisol levels has not been conclusively established. We conducted a systematic review using the PRISMA Guidelines based on comprehensive database searches for 1) studies of OSA patients compared to controls in whom cortisol was measured and 2) studies of OSA patients treated with continuous positive airway pressure (CPAP) in whom cortisol was measured pre and post treatment. Five electronic databases were searched along with the reference lists of retrieved studies. The primary outcomes were 1) differences in cortisol between OSA and control subjects and 2) differences in cortisol pre-post CPAP treatment. Sampling methodology, sample timing and exclusion criteria were evaluated. Fifteen studies met the inclusion criteria. Heterogeneity of studies precluded statistical pooling. One study identified differences in cortisol between OSA patients and controls. Two studies showed statistically significant differences in cortisol levels pre-post CPAP. The majority of studies were limited by assessment of cortisol at a single time point. The available studies do not provide clear evidence that OSA is associated with alterations in cortisol levels or that treatment with CPAP changes cortisol levels. Methodological concerns such as infrequent sampling, failure to match comparison groups on demographic factors known to impact cortisol levels (age, body mass index; BMI), and inconsistent control of variables known to influence HPA function may have limited the results.

prs.rt("abs_end");Obstructive sleep apnea; Cortisol; Continuous positive airway pressure; Systematic review

Figures and tables from this article:

Fig. 1. PRISMA trial flow used to identify studies for detailed analysis of cortisol in 1) patients with obstructive sleep apnea and healthy controls and 2) patients with obstructive sleep apnea before and after treatment with continuous positive airway pressure. AHI = Apnea hypopnea index; CPAP = Continuous positive airway pressure.

View Within ArticleTable 1. The 7 included studies of cortisol in patients with OSA versus controls.

View table in articleNa = No information; OSA = Obstructive sleep apnea; BMI = Body mass index; AHI = Apnea hypopnea index; EDS = Excessive daytime sleepiness; w = with; wo = without.

View Within ArticleTable 2. The 8 included studies of cortisol in patients with OSA treated with CPAP.

View table in articleNa = No information; OSA = Obstructive sleep apnea; BMI = Body mass index; AHI = Apnea hypopnea index; EDS = Excessive daytime sleepiness; SE = Standard error of the mean; w = with; wo = without.

View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.

prs.rt('data_end');

View the original article here

Saturday, June 2, 2012

Are sleep education programs successful? The case for improved and consistent research efforts

University of South Australia, Centre for Sleep Research, PO Box 2471, Adelaide SA 5000, AustraliaReceived 3 June 2011. Revised 2 August 2011. Accepted 2 August 2011. Available online 20 November 2011.View full text Sleep duration and quality are associated with a range of neuropsychological and psychosocial outcomes in children and adolescents but community awareness of this is low. A small body of literature on sleep education programs in children and adolescents delivered through school-based programs is attempting to address this. A review of the literature found only 8 studies and 4 pilot studies in abstract form. This paper presents these sleep education programs and evaluates their effectiveness. In general, findings suggest that when sleep knowledge was measured it was increased in most programs. However this did not necessarily equate to sleep behaviour change such as increased sleep duration or improved sleep hygiene. Reasons for this are discussed and may include motivation and readiness to change, salience to the individual, delivery, content, time allocation, or methodological underpinnings. This paper attempts to understand this and assess how best to improve future sleep education programs from a theoretical perspective. Specifically, it considers the theory of planned behaviour which may assist in ensuring maximum efficacy for the current and future development of sleep education programs.

prs.rt("abs_end");Sleep education; Motivation; Sleep duration; Sleep hygiene; Paediatric sleep; Adolescent sleep

Figures and tables from this article:

Fig. 1. Representation of an integrated model of behaviour change (Adapted from Ajzen50).

View Within ArticleTable 1. Downs and Black (1998)28 criteria used in the methodological quality evaluation of the reviewed studies.

View table in articleAll items scored 0 or 1, except “description of principal confounders”, which scored 0, 1, or 2.

View Within ArticleTable 2. General characteristics of school sleep education programs.

View table in article* ACES = Australian centre for education in sleep, RCT = randomised controlled trial, STEPS = sleep treatment and education program for students.

View Within ArticleTable 3. Summary of measures, design and results.

View table in articleACES = Australian centre for education in sleep, DST = delayed sleep timing, PSQI = Pittsburgh sleep quality index, RCT = randomised controlled trial, STEPS = sleep treatment and education program for students.

View Within ArticleTable 4. Quality of studies (not including abstracts).

View table in articleView Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.

prs.rt('data_end');

View the original article here

Thursday, October 20, 2011

Spectacles de recherche alerte médicale systèmes ajouter confort


Les systèmes d'alerte médicale a d'abord touché conscience américaine dans les années 1980, avec la permission de TV commercial avec une femme âgée bouche une phrase désormais célèbre de huit-mot après avoir perdu son équilibre et tombent sur le sol.

Des systèmes d'alarme maison médicale consistent généralement en une unité de base et un pendentif qui peut être porté comme un bracelet ou un collier. Dans les situations d'urgence possibles où un téléphone est hors de la plage, l'utilisateur aurait appuyez sur le bouton et le hangar. En réponse, un signal serait être donné à l'unité de base de mesure, qui à son tour contacte un poste de contrôle central. Un représentant de la station de mesure serait alors communiquer avec l'utilisateur par le biais du hangar pour déterminer la gravité du personnel médical de la situation et ou urgents.

Convaincre le nombre de personnes âgées sur les aspects pratiques d'alerte médicale l'utilisation d'un tel système peut être un hard sell. Une des sources plus importantes pour cette limitation peut être attribuée à un sentiment de perte de l'indépendance. Cependant, médicale des systèmes d'alarme peuvent étendre en réalité l'indépendance du senior en fournissant un sentiment de sécurité aux familles et aux proches aidants qui pourraient être une personne à contacter leurs proches qu'ils endommagent la maison il y a et qui n'étaient pas capables d'atteindre le téléphone.

Quelques faits :

-60 % des visites qu'un personne âgée de plus de 65 ans à la salle d'urgence sont le résultat d'une diminution dans ou autour de la maison, selon le Conseil de sécurité de produits aux consommateurs.

-30 % de tous les gens âgés de plus de 65 ans tombent chaque année, conformément à l'Académie américaine des chirurgiens orthopédistes.

-Le taux de mortalité est cinq fois plus élevé pour les personnes qui soumettent une incapacité pendant 12 heures auxmédiaspar rapport à l'aide de GI, selon une étude menée par le New England Journal of Medicine.

En l'an 2000, les patients âge de 65 ans et plu représentent 40 % de tous les rejets de l'hôpital. Avec les 65 et au groupe d'âge devrait augmenter de 35 % à 54 millions de personnes médical d'ici 2020, sont les services et les taux d'hospitalisation pour les personnes âgées augmenteront considérablement aussi bien.

Une façon de la quantité de temps passé à l'hôpital est de réduire médicale en vous abonnant à un système d'avertissement. Une étude de la médecine New England Journal of Medicine a montré d'alerte les utilisateurs avaient moins et plus courts séjours à l'hôpital après s'abonner à un service. Médicale une autre étude a conclu que le taux de mortalité de systèmes de réduction et d'avertissement, avec presque 60 % entaillée utilisation des hôpitaux.

Alarme médicale pour les personnes concernées qu'un abonné pourrait compromettre leur indépendance, recherche médicale suggère des systèmes d'alerte ont l'effet inverse. Utilisateurs du système d'alerte médicale et leurs familles ont montré qu'un sentiment de sécurité, qui est d'accroître la qualité de vie et les sentiments d'indépendance peut entraîner.

Ressources supplémentaires :
Bernstein, m. « technicité » réponse d'urgence personnelles systèmes réduisent les coûts et améliorer les résultats, 2000.
Département de l'Université de Floride de l'ergothérapie. Utilisation de systèmes de personnel d'intervention d'urgence par des personnes âgées, handicapées, 2005.




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Advancements in Stem Cell Research and Multiple Sclerosis Treatments

Multiple sclerosis is a disease of the immune system that affects the central nervous system, or brain and spinal cord. A form of auto-immune disease, the disease damages the nerves and may affect separate or multiple parts of the body, causing pain and severe limitation to movement, ability, and quality of life.


The disease causes damage and destruction to the protective covering (myelin sheath) that surrounds nerve cells. Damage to the myelin sheath severely slows or interrupts nerve impulses, causing intense pain and inability to control movement. Individuals diagnosed with multiple sclerosis experience episodes of inflammation that cause the body's immune cells to attack the nervous system.


Stem Cell Technologies and Multiple Sclerosis
In recent months, treating a patient who has been diagnosed with multiple sclerosis with their own immune system stem-cells has shown promise in some clinical trials where severe nerve cell damage has not yet occurred.


Clinical trials developed at the Northwestern University Feinberg School Of Medicine in Chicago removed patient's stem-cells in bone marrow, injected chemicals to destroy damaged immune cells and then re-injected the stem-cells into the patient's bodies. Three years later, none of the 23 individuals who engaged in the clinical trials experienced further deterioration, while 17 of them showed some improvement.


In further studies, adult stem-cells that have been taken from a patient's fatty tissues have shown promise in reducing clinical manifestation of the disease process. Clinical trials using mesenchymal stem-cells showed improvement, according to the Journal Of Translational Medicine, describing studies performed at the University of California San Diego. Mesenchymal stem-cells have been shown to reduce or stop immune activation of cells and target specific areas where tissue damage had occurred.


Use of stem-cell technologies to treat multiple sclerosis is designed to literally "reset" immune system function and is focusing on reversing or slowing early diagnosis of multiple sclerosis. Recently, an international symposium (Stem Cell Transplantation in Multiple Sclerosis: Sharing The Experience) was conducted in Moscow, Russia to discuss perspectives in new methods of treating multiple sclerosis through autologous hematopoietic (bone marrow stem-cells that may 'morph' or develop into a variety of stem cell types)stem-cell transplantation combined with high dose immunosuppressive therapies.


The Future of Treatment
In recent months, Brainstorm Cell Therapeutics, Inc., has developed a therapeutic approach for potential treatment of multiple muscular conditions including Parkinson's disease, ALS and multiple-sclerosis. Multiple sclerosis treatments are currently being conducted on mouse models, with results published in the Journal Of Molecular Neuroscience.


Benefits of such treatment offer individuals diagnosed with multiple-sclerosis, especially those diagnosed early, with renewed neural and muscular function, reduced symptoms and enhanced quality of life. News articles abound with stories of various stages of recovery of those who have undergone stem-cell treatment for multiple-sclerosis, some who have even recovered the ability to walk.


From Australia to Europe, individuals undergoing clinical trials of stem-cell therapy have been showing a 60 to 80% chance of slowing the disease process, while some may enjoy the benefits of reversing the disease in its entirety. While there is no cure as yet for multiple-sclerosis, stem-cell treatments that focus on repair and regeneration of the central nervous system offer hope to individuals suffering from neural damage around the globe.


This post was made using the Auto Blogging Software from WebMagnates.org This line will not appear when posts are made after activating the software to full version.

Advancements in Stem Cell Research and Multiple Sclerosis Treatments


Multiple sclerosis is a disease of the immune system that affects the central nervous system, or brain and spinal cord. A form of auto-immune disease, the disease damages the nerves and may affect separate or multiple parts of the body, causing pain and severe limitation to movement, ability, and quality of life.

The disease causes damage and destruction to the protective covering (myelin sheath) that surrounds nerve cells. Damage to the myelin sheath severely slows or interrupts nerve impulses, causing intense pain and inability to control movement. Individuals diagnosed with multiple sclerosis experience episodes of inflammation that cause the body's immune cells to attack the nervous system.

Stem Cell Technologies and Multiple Sclerosis

In recent months, treating a patient who has been diagnosed with multiple sclerosis with their own immune system stem-cells has shown promise in some clinical trials where severe nerve cell damage has not yet occurred.

Clinical trials developed at the Northwestern University Feinberg School Of Medicine in Chicago removed patient's stem-cells in bone marrow, injected chemicals to destroy damaged immune cells and then re-injected the stem-cells into the patient's bodies. Three years later, none of the 23 individuals who engaged in the clinical trials experienced further deterioration, while 17 of them showed some improvement.

In further studies, adult stem-cells that have been taken from a patient's fatty tissues have shown promise in reducing clinical manifestation of the disease process. Clinical trials using mesenchymal stem-cells showed improvement, according to the Journal Of Translational Medicine, describing studies performed at the University of California San Diego. Mesenchymal stem-cells have been shown to reduce or stop immune activation of cells and target specific areas where tissue damage had occurred.

Use of stem-cell technologies to treat multiple sclerosis is designed to literally "reset" immune system function and is focusing on reversing or slowing early diagnosis of multiple sclerosis. Recently, an international symposium (Stem Cell Transplantation in Multiple Sclerosis: Sharing The Experience) was conducted in Moscow, Russia to discuss perspectives in new methods of treating multiple sclerosis through autologous hematopoietic (bone marrow stem-cells that may 'morph' or develop into a variety of stem cell types)stem-cell transplantation combined with high dose immunosuppressive therapies.

The Future of Treatment

In recent months, Brainstorm Cell Therapeutics, Inc., has developed a therapeutic approach for potential treatment of multiple muscular conditions including Parkinson's disease, ALS and multiple-sclerosis. Multiple sclerosis treatments are currently being conducted on mouse models, with results published in the Journal Of Molecular Neuroscience.

Benefits of such treatment offer individuals diagnosed with multiple-sclerosis, especially those diagnosed early, with renewed neural and muscular function, reduced symptoms and enhanced quality of life. News articles abound with stories of various stages of recovery of those who have undergone stem-cell treatment for multiple-sclerosis, some who have even recovered the ability to walk.

From Australia to Europe, individuals undergoing clinical trials of stem-cell therapy have been showing a 60 to 80% chance of slowing the disease process, while some may enjoy the benefits of reversing the disease in its entirety. While there is no cure as yet for multiple-sclerosis, stem-cell treatments that focus on repair and regeneration of the central nervous system offer hope to individuals suffering from neural damage around the globe.




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Obtaining Sports Medicine Information - List Of Excellent Research Journals


There are numerous research journals of sports medicine that cater to an international readership. Sports have become professional and more and more people are taking it up as a means to earn a living, as well as fame. As a result of the competitive nature of sports, there is more practice involved and consequently more injuries are also being suffered by the sports persons. The demand for medicine especially applicable to sports has therefore catapulted. New research and the number of studies that are being conducted in this field has increased manifold.

As there is vast amount of research information available nowadays, the research publications have also gone up in number. The print media, online media

(both free to use and paid subscription) as well as specialised books, all have started providing increased coverage to research journals of sports medicine. Research in Sports Medicine is a known name in the sports medicine field, since several years. Professionals practising sports medicine find a platform to discuss their research in this publication. International sports medicine practitioners share their research work in prevention as well as management and also rehabilitation of sports injuries; injuries that occur due to exercises and physical activities and also injuries because of occupational problems.

Among other reputed research journals of sports medicine, the official publication of American Orthopedic Society for Sports Medicine (AOSSM) has pride of place. American Journal of Sports Medicine as it is called is a scientific publication wherein the research work is reviewed by peers.

Research journals of sports medicine have a key role to play as they are also a forum for practitioners to learn about unbiased opinions on research pertaining to orthopaedic sports medicine. As the information available is scientific and correct, they are able to update their knowledge and make well informed decisions.

Science and Sports is published by the French Society of Sports Medicine. This research journal is a reliable source of information for work being conducted not just in scientific, and medical but also applied technical research, related to internal medicine, psychology, biomechanics, traumatology, sociology and technology; as applicable to sports and on a broader level all physical activities.

Research journals of sports medicine are an important part of the medical field to disseminate information. New developments come up practically each day and new techniques emerge; the research journals of medical information provide the right platform to present them before the world. The sports medicine practitioners do not have to search for the information all over as they know it is available in these reputed research journals of sports medicine.




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